Polynucleotide treatment at central London
Polynucleotides Treatments
Treatments are exclusively administered by GMC-registered medical professionals.
20 Years of Clinical Confidence
Dr Vahe Clinic has proudly delivered two decades of medical excellence, providing patients with safe, effective, and personalised treatments.
Award-Winning Standards
Our clinic has been recognised with multiple awards over the years, reflecting our unwavering commitment to exceptional patient care and clinical outcomes.
GMC and Professional Body Registered Professionals
Every treatment is carried out exclusively by GMC-registered doctors and qualified practitioners , ensuring medical integrity, safety, and the highest standard of care you can trust.
Polynucleotides
What They Are and Why They Matter in Aesthetics
Polynucleotides are an exciting new development in aesthetic medicine – offering a regenerative approach to skin rejuvenation by working with your body’s natural processes. These innovative treatments are designed to improve skin quality from within, making them an excellent choice for clients seeking natural-looking results and long-term skin health.
At their core, polynucleotides are biological molecules made up of nucleotides, which are the basic units of DNA and RNA – the building blocks of all living cells. In aesthetic treatments, polynucleotides are typically derived from purified DNA fragments sourced from salmon or trout. These fragments are biocompatible with human tissue, meaning they are safe, well-tolerated, and effective in stimulating the skin’s own repair systems.
How Do Polynucleotide Treatments Work?
When injected into the skin, polynucleotides act as biostimulators – encouraging your skin to repair, regenerate, and restore itself. Rather than simply filling or plumping the skin like traditional dermal fillers, polynucleotides target the underlying health of the skin by:
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Activating fibroblasts – the skin cells responsible for producing collagen and elastin. This helps to improve firmness, elasticity, and overall skin texture.
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Encouraging tissue repair and cellular regeneration, making them ideal for treating tired, damaged, or ageing skin.
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Reducing inflammation, which helps calm irritated or sensitive areas.
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Attracting and retaining moisture, improving hydration and giving the skin a dewy, fresh appearance.
Over time, the skin becomes more resilient, luminous, and visibly refreshed. Results build gradually and naturally, with improvements continuing to develop over several weeks following treatment.
Treatable Areas with Polynucleotides
Before & After
Polynucleotides are an advanced regenerative treatment designed to stimulate your skin’s natural healing processes. Unlike fillers, they don’t add volume but instead work beneath the surface to improve skin quality, texture, and hydration. Here’s how each area can benefit:
Face
Polynucleotides are ideal for full-face rejuvenation, offering a natural alternative to traditional injectables. They work to enhance overall skin tone, boost hydration, and improve elasticity, giving your complexion a healthier, more radiant look. This treatment is perfect for those looking to refresh tired, dull, or ageing skin without changing their facial features. Results develop gradually, with noticeable improvements in smoothness and glow.
Under-Eye Area
The delicate under-eye region is one of the first areas to show signs of ageing, often with dark circles, hollowness, and fine lines. Polynucleotide treatments are gentle yet powerful in improving this area, reducing pigmentation, boosting hydration, and thickening the skin naturally. It’s especially effective for clients who want to avoid tear trough fillers but still wish to brighten and revitalise their eyes.
Neck
The neck is a commonly overlooked area but can quickly reveal ageing through fine lines, crepey texture, and skin laxity. Polynucleotides help to firm and revitalise this area by encouraging collagen production and cellular repair. With regular treatment, the neck appears smoother, tighter, and more youthful, making it a favourite for those seeking non-surgical anti-ageing options.
Décolletage (Chest)
Sun exposure and time can lead to pigmentation, fine lines, and thinning skin across the chest. Polynucleotides offer a gentle solution to rejuvenate this area by deeply hydrating the skin and supporting tissue repair. The treatment enhances radiance and smoothness, making the décolletage appear fresher and more evenly toned.
Hands
The hands often betray our age, with thinning skin, visible veins, and fine lines. Polynucleotide treatments help to restore moisture, firmness, and skin density, giving the hands a plumper, healthier appearance. It’s a subtle yet highly effective way to maintain a youthful look beyond the face.
Abdomen
After pregnancy or weight fluctuations, the skin on the stomach can lose its firmness and resilience. Polynucleotides support collagen production and tissue regeneration, helping to gradually tighten and revitalise the abdominal area. It’s a non-invasive way to enhance tone and skin texture over time.
Décolletage (Chest)
Sun exposure and time can lead to pigmentation, fine lines, and thinning skin across the chest. Polynucleotides offer a gentle solution to rejuvenate this area by deeply hydrating the skin and supporting tissue repair. The treatment enhances radiance and smoothness, making the décolletage appear fresher and more evenly toned.
Scalp
Polynucleotides can be used on the scalp to improve overall skin health, reduce inflammation, and support hair restoration protocols. When applied alongside other hair treatments, they help create an optimal environment for stronger, healthier hair growth, making it a valuable option for clients concerned about thinning or hair loss.
Your Journey with Polynucleotides
We offer more than just a treatment — we provide a supportive and professional experience designed around you. Here’s what to expect at every stage of your polynucleotide rejuvenation journey:
Personal Consultation with OBSERV® 520x Skin Analysis
Your journey begins with a detailed, face-to-face consultation carried out by one of our experienced medical professionals. As part of this process, we use the latest OBSERV® 520x skin analysis technology — an advanced diagnostic system that provides a detailed, 360-degree view of your skin’s condition beneath the surface.
This non-invasive scanner uses multiple light modes to reveal concerns such as dehydration, pigmentation, oil imbalance, enlarged pores, textural changes, and early signs of ageing — even those not yet visible to the naked eye. The analysis allows us to make truly informed decisions and tailor your polynucleotide treatment with precision.
With a clearer understanding of your skin’s true needs, we’ll design a personalised treatment plan that targets specific issues, enhances skin quality, and delivers long-lasting, regenerative results.
Tailored Treatment Plan
Every client is different — that’s why we never take a one-size-fits-all approach. Based on your consultation, we’ll map out a course of treatment that aligns with your skin’s needs and your desired outcomes. This may include one or several sessions, depending on your goals and response to treatment.
Treatment Session
On the day of your appointment, the treatment area will be gently cleansed and prepared. The polynucleotide solution is then carefully injected using fine needles to deliver the product precisely where it's needed. Most clients find the procedure comfortable and quick, with minimal downtime.
24/7 Client Support
Every client is different — that’s why we never take a one-size-fits-all approach. Based on your consultation, we’ll map out a course of treatment that aligns with your skin’s needs and your desired outcomes. This may include one or several sessions, depending on your goals and response to treatment.
Follow-Up Appointments (If Needed)
As part of your personalised care plan, we may recommend follow-up visits to monitor your progress and adjust your treatment if necessary. Your satisfaction and results matter, and we’re here to ensure your skin continues to improve long after your first session.
Dr Vahe Karimyan
MD, MS, PhD
GMC: 7021759
“Polynucleotides have completely changed the way we approach skin rejuvenation. They’re not just another quick fix — they’re naturally derived molecules that work in harmony with your skin to repair, hydrate, and restore. What I genuinely love about them is how they encourage your skin to heal and regenerate from within, helping to rebuild strength and radiance over time. Unlike many treatments that only mask imperfections on the surface, polynucleotides go deeper, targeting the root causes of skin ageing and dullness. The results feel more natural, more lasting — and the skin just looks healthier, calmer, and more balanced. It’s a treatment that respects the skin’s natural rhythm, and that’s something I truly value.”
Real Stories, Real Results
Whether it’s your first visit or a continued path to better skin, hear from those who’ve walked this road with us.
The Prices
Polynucleotide Treatment Pricing at Dr. Vahe Clinic
Experience the rejuvenating benefits of Polynucleotide therapy at Dr. Vahe Clinic.
This advanced treatment promotes natural skin regeneration and hydration, helping to restore a youthful, radiant appearance.
Our pricing options are:
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Single session: £350
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Package of three sessions: £900
The cost reflects the expert care provided by our skilled medical team and the use of premium, clinically proven products. Delivered in a professional and comfortable setting, each treatment is customised to meet your individual needs for optimal results.
Choose Dr Vahe Clinic for a trusted and personalised approach to skin revitalisation.
£350
Experience a truly personalised skin assessment — powered by OBSERV® 520x technology. Using advanced light settings (including daylight, cross-polarised, and UV), we reveal what’s happening beneath the surface. Complimentary consultation with full refund if treatment isn’t suitable.
CHOOSE YOUR CONSULTATION TYPE
We believe in the power of personalised consultations to ensure every treatment aligns with your goals, health needs, and lifestyle. Whether you're exploring aesthetic enhancements, considering a surgical option, seeking medical advice, or beginning your weight loss journey, our consultations are designed to provide clinical clarity and a supportive experience. Each consultation is led by a qualified specialist and includes a thorough assessment, ensuring you feel informed and confident at every stage.