Profhilo vs Dermal Fillers: What’s the Difference – and Which Type of Profhilo Is Best for You?

As we age, our skin naturally loses elasticity, hydration, and that youthful glow. Fine lines, dullness, and sagging are common concerns – but modern non-surgical treatments like Profhilo and dermal fillers offer effective solutions to rejuvenate and refresh the skin.

While both treatments involve hyaluronic acid (HA), they work in very different ways. In this guide, we’ll explain the key differences between Profhilo and dermal fillers, and help you decide which treatment – or combination – may be right for your skin. We’ll also explore the two types of Profhilo now available: Classic Profhilo and Profhilo Structura.

What Is Profhilo?

Profhilo is an injectable skin treatment made from pure hyaluronic acid. Unlike topical HA creams that only hydrate the surface, Profhilo is injected beneath the skin where it spreads evenly and deeply hydrates from within. It also stimulates the natural production of collagen and elastin, improving skin tone, texture, and firmness.

Often referred to as an "injectable moisturiser," Profhilo restores skin radiance and elasticity without changing facial structure.

Profhilo Benefits

• Deep skin hydration

• Increased collagen and elastin production

• Improved skin elasticity and firmness

• Reduction in fine lines and crepey texture

• Healthier, more youthful skin glow

Profhilo is ideal for areas including the face, neck, décolletage, hands, arms, and more.

Classic Profhilo vs Profhilo Structura

With the introduction of Profhilo Structura, patients now have two options tailored to different skin concerns:

Classic Profhilo

• Best for mild to moderate ageing

• Thin, fluid texture that spreads evenly

• Targets hydration, fine lines, and skin laxity

• Injected using the BAP (Bio Aesthetic Points) technique

Profhilo Structura

• Designed for more advanced signs of ageing

• Thicker consistency with structural support

• Provides subtle lift and improved firmness

• Suitable for midface hollowing and skin sagging

Which should you choose?

• Go for Classic Profhilo if your skin needs hydration and glow.

• Choose Structura for more definition and support in areas affected by volume loss.

Profhilo vs Dermal Fillers

How Is Profhilo Different from Dermal Fillers?

Although both Profhilo and fillers use hyaluronic acid, they serve very different purposes:

Profhilo	Dermal Fillers
Hydrates and stimulates collagen	Adds volume and definition
No change to facial shape	Can sculpt or contour features
Spreads evenly under skin	Stays localised to injection site
Biocompatible and BDDE-free	Contains BDDE cross-linking agent
Results in improved skin quality	Results in plumper, reshaped areas

Dermal fillers are ideal for lips, cheeks, jawline, and under-eye hollows, while Profhilo works best for overall skin rejuvenation.

Profhilo Treatment Process

• Quick, minimally invasive treatment

• Requires two sessions, four weeks apart

• Maintenance every 6 months recommended

• Minimal downtime (mild swelling or bumps may occur temporarily)

Aftercare Tips:

• Avoid strenuous exercise for 24 hours

• No saunas or steam rooms for 48 hours

• Avoid active skincare ingredients (like retinol or vitamin C) for 24 hours

Is Profhilo Safe?

Yes. Profhilo is FDA and MHRA approved and made from pure hyaluronic acid with no chemical cross-linking agents. It's safe, biocompatible, and has minimal side effects when administered by a qualified medical professional.

Can Profhilo Be Combined with Other Treatments?

Absolutely. Profhilo works beautifully alongside:

• Botulinum toxin (Botox) for dynamic lines

• Dermal fillers for added volume

• Microneedling or skin boosters for enhanced texture

Your practitioner will guide you in designing a treatment plan tailored to your goals.

Who Is Profhilo Suitable For?

Profhilo is suitable for men and women showing early or moderate signs of ageing, including:

• Dehydrated or thinning skin

• Dull complexion

• Fine lines and loss of elasticity

• Mild sagging or hollowing

It’s also a great preventative treatment for those looking to maintain youthful, glowing skin.

Ready to Refresh Your Skin?

Whether you’re new to injectables or exploring your next aesthetic treatment, Profhilo is a fantastic option for natural skin rejuvenation. Book a consultation with our experienced team to find out whether Classic Profhilo or Profhilo Structura is right for you.

Achieve radiant, hydrated, and firmer skin – without altering your natural features.

Contact us today to book your Profhilo consultation.